N-(9-Fluorenylmethoxycarbonyl) Doxorubicin

• 产品号: F472430
• CAS号: 136582-53-1
• 分子式: C42H39NO13
• 分子量: 765.75796

产品别名

• 标题: N-(9-Fluorenylmethoxycarbonyl) Doxorubicin
• IUPAC标准名: 9H-fluoren-9-ylmethyl N-[(2S,3S,4S,6S)-3-hydroxy-2-methyl-6-{[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy}oxan-4-yl]carbamate
• IUPAC传统名: 9H-fluoren-9-ylmethyl N-[(2S,3S,4S,6S)-3-hydroxy-2-methyl-6-{[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy}oxan-4-yl]carbamate
• 别名: (8S,10S)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione

产品登记号

• CAS号: 136582-53-1

产品性质

• 外观: Red Solid
• 溶解度: Dichloromethane

产品详细信息

详细说明 (English)

Used in the preparation of a modified Doxorubicin (ANG1007) and Etoposide (ANG1009), useful due to their brain penetration ability.

参考文献

• Che, C. et al.: J. Med. Chem. 53, 2814 (2010)