Flavopiridol hydrochloride

• 产品号: F373000
• CAS号: 131740-09-5
• 分子式: C21H21Cl2NO5
• 分子量: 438.30114
• 保 存: -20°C Freezer

产品别名

• 标题: Flavopiridol hydrochloride
• IUPAC标准名: 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one hydrochloride
• IUPAC传统名: flavopiridol hydrochloride
• 别名: MDL 107826A; rel-(-)-2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one Hydrochloride; NSC 649890; Alvocidib Hydrochloride; HL 275

产品登记号

• CAS号: 131740-09-5

产品性质

• 外观: Yellow Solid
• 熔点: 183-187°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

An inhibitor of cyclin-dependent kinases; the (-)-cis form induces apoptosis in certain tumor cells.

参考文献

• Senderowicz, A.M., et al.: J. Clin. Oncol., 16, 2986 (1998)
• Thomas, J.P., et al.: Cancer Chemother. Pharmacol., 50, 465 (1998)
• Raju, U., et al.: Cancer Res., 63, 3263 (1998)
• Pumfery, A., et al.: Curr. Pharm. Des., 12, 1949 (1998)