Fidexaban-d3

• 产品号: F335502
• 分子式: C25H24F2N6O5
• 分子量: 526.4920664

产品别名

• 标题: Fidexaban-d3
• IUPAC标准名: 2-{[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-{3-[1-(^2H₃)methyl-4,5-dihydro-1H-imidazol-2-yl]phenoxy}pyridin-4-yl](methyl)amino}acetic acid
• IUPAC传统名: {[2-(5-carbamimidoyl-2-hydroxyphenoxy)-3,5-difluoro-6-{3-[1-(^2H₃)methyl-4,5-dihydroimidazol-2-yl]phenoxy}pyridin-4-yl](methyl)amino}acetic acid
• 别名: ZK 807834-d3; Fidexaban-d3; CI 1031-d3; N-[2-[5-(aminoiminomethyl)-2-hydroxyphenoxy]-6-[3-[4,5-dihydro-1-(methyl-d3)-1H-imidazol-2-yl]phenoxy]-3,5-difluoro-4-pyridinyl]-N-methylglycine

产品详细信息

详细说明 (English)

A labelled direct inhibitor of factor Xa (FXa); anticoagulant. It has been shown to reduce ex-vivo arterial thrombus formation and factor-X activity in a dose-dependent manner.

参考文献

• Zafar, M.U. et al.: Thromb. Haemost., 97, 487 (2007)
• McClanahan, T.B. et al.: Eur. J. Pharmacol., 432, 187 (2007)
• Chi, L. et al.: Pharmacol., 64, 76 (2007)