Fialuridine 5'-Monophosphate

• 产品号: F335010
• CAS号: 99891-31-3
• 分子式: C9H11FIN2O8P
• 分子量: 452.0688742

产品别名

• 标题: Fialuridine 5'-Monophosphate
• IUPAC标准名: {[(2R,3S,5R)-4-fluoro-3-hydroxy-5-(5-iodo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid
• IUPAC传统名: [(2R,3S,5R)-4-fluoro-3-hydroxy-5-(5-iodo-2,4-dioxo-3H-pyrimidin-1-yl)oxolan-2-yl]methoxyphosphonic acid
• 别名: 1-(2-Deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione

产品登记号

• CAS号: 99891-31-3

产品详细信息

详细说明 (English)

Fialuridine 5’-Monophosphate (FIAUMP) is the phosphorylated derivative and major metabolite of the antiviral agent Fialuridine (F335000). Studies show that purified mammalian DNA polymerases were able to incorporate FIAUMP into the nascent DNA chain durin

参考文献

• McLaren, C. et al.: Int. Cong. Ser., 667, 57 (1985)
• Lewis, W. et al.: BIochem., 33, 14620 (1985)