Febuxostat Acyl-β-D-glucuronide

• 产品号: F229030
• CAS号: 1351692-92-6
• 分子式: C22H24N2O9S
• 分子量: 492.49896
• 保 存: Refrigerator, Under Inert Atmosphere

产品别名

• 标题: Febuxostat Acyl-β-D-glucuronide
• IUPAC标准名: (2S,3S,4S,5R,6S)-6-{2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyloxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC传统名: (2S,3S,4S,5R,6S)-6-{2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyloxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• 别名: 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylate β-D-Glucopyranuronic Acid; 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylate β-D-Glucopyranuronic Acid

产品登记号

• CAS号: 1351692-92-6

产品性质

• 外观: White Solid
• 熔点: 172-175°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A metabolite of Febuxostat (F229000), a novel nonpurine selective inhibitor of Xanthin Oxidase.

参考文献

• Grabowski, B., et al.: J. Clin. Pharmacol., 51, 189 (2011)
• Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (2011)
• Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2011)
• Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2011)
• Tomlinson, B., et al.: Curr. Opi