Ezetimibe Phenoxy β-D-Glucuronide

• 产品号: E975030
• CAS号: 190448-57-8
• 分子式: C30H29F2NO9
• 分子量: 585.5493664
• 保 存: Hygroscopic, -20°C Freezer, Under inert atmosphere

产品别名

• 标题: Ezetimibe Phenoxy β-D-Glucuronide
• IUPAC标准名: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC传统名: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• 别名: EZM-G; Sch 58235 Glucuronide; 4-[(2S,3R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid; Ezetimibe Phenoxy Glucuronide; Sch 60663

产品登记号

• CAS号: 190448-57-8

产品性质

• 外观: White Solid
• 熔点: 140-150°C
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under inert atmosphere

产品详细信息

详细说明 (English)

Phase-II metabolite of Ezetimibe, an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.This compound is very hygroscopic. Handle with care.

参考文献

• van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997)
• van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)