(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

• 产品号: E917350
• CAS号: 110351-94-5
• 分子式: C13H13NO5
• 分子量: 263.24602

产品别名

• 标题: (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
• IUPAC标准名: (4S)-4-ethyl-4-hydroxy-1H,3H,4H,6H,7H,8H,10H-pyrano[3,4-f]indolizine-3,6,10-trione
• IUPAC传统名: (4S)-4-ethyl-4-hydroxy-1H,7H,8H-pyrano[3,4-f]indolizine-3,6,10-trione
• 别名: (S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

产品登记号

• CAS号: 110351-94-5

产品详细信息

详细说明 (English)

(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate in the synthesis of Irinotecan (I767500) and Camptothecin (C175150) analogs.

参考文献

• Hsiang, Y., et al.: J. Biol. Chem., 260, 14873 (1985)
• Bao, Y., et al.: Chin. J. Med. Chem., 18, 263 (1985)
• Miao, Z., et al.: Bioorg. Med. Chem., 16, 1493 (1985)