4'-Ethyl-7',8'-dihydro-4'-hydroxy-spiro[1,3-dioxolane-2,6'(3'H)-[1H]pyrano[3,4-f]indolizine]-3',10'(4'H)-dione-d5

• 产品号: E917312
• 分子式: C15H17NO6
• 分子量: 307.29858

产品别名

• 标题: 4'-Ethyl-7',8'-dihydro-4'-hydroxy-spiro[1,3-dioxolane-2,6'(3'H)-[1H]pyrano[3,4-f]indolizine]-3',10'(4'H)-dione-d5
• IUPAC标准名: 4'-(^2H₅)ethyl-4'-hydroxy-1',3',4',7',8',10'-hexahydrospiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione
• IUPAC传统名: 4'-(^2H₅)ethyl-4'-hydroxy-7',8'-dihydro-1'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione
• 别名: (±)-4'-Ethyl-7',8'-dihydro-4'-hydroxy-spiro[1,3-dioxolane-2,6'(3'H)-[1H]pyrano[3,4-f]indolizine]-3',10'(4'H)-dione-d5

产品性质

• 外观: Off-white Solid
• 溶解度: Dichloroform
• 溶解度: Methanol

产品详细信息

详细说明 (English)

Used in the preparation of Camptothecin and Homocamptothecin derivatives, for their therapeutic use as antitumor agents.

参考文献

• Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986)
• Miller, K.D., et al.: Invest. New Drugs, 22, 69 (1986)
• Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (1986)
• Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005)