7-Ethyl-d3-camptothecin

• 产品号: E900832
• 分子式: C22H20N2O4
• 分子量: 376.4052

产品别名

• 标题: 7-Ethyl-d3-camptothecin
• IUPAC标准名: (19S)-19-ethyl-10-[(2,2,2-^2H₃)ethyl]-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
• IUPAC传统名: (19S)-19-ethyl-10-[(2,2,2-^2H₃)ethyl]-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
• 别名: (4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione-d3; SN 22-d3; 7-Ethyl-d3-20(S)-camptothecin

产品性质

• 外观: Beige Solid
• 溶解度: N,N-Dimethylformamide
• 溶解度: Dimethyl Sulfoxide

产品详细信息

详细说明 (English)

An anticancer drug, showed strong activity against various murine tumors. A Labelled camptothecin(CPT) derivative as antineoplastic agent against drug-resistant tumors.

参考文献

• Miyake, K., et al.: Cancer Res., 59, 8 (1999)
• Brangi, M., et al.: Cancer Res., 59 5938 (1999)
• Bom, D., et al.: J. Med. Chem., 43, 3970 (1999)
• Gamcsik, M., et al.: Mol. Cancer Ther., 1, 11 (2001).