Estrone 3-O-Sulfamate

• 产品号: E889060
• CAS号: 148672-09-7
• 分子式: C18H23NO4S
• 分子量: 349.44452
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Estrone 3-O-Sulfamate
• IUPAC标准名: (1S,10R,11S,15S)-15-methyl-14-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-5-yl sulfamate
• IUPAC传统名: (1S,10R,11S,15S)-15-methyl-14-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-5-yl sulfamate
• 别名: Estrone 3-Sulfamate; 3-[(Aminosulfonyl)oxy]estra-1,3,5(10)-trien-17-one; Estrone O-Sulfamate; EMATE; Estrone Sulfamate

产品登记号

• CAS号: 148672-09-7

产品性质

• 外观: White to Off-White Solid
• 熔点: 195-197°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.

参考文献

• Woo, L.W., et al.: J. Med. Chem., 41, 1068 (1998)