Erythromycin A Oxime (Roxithromycin Impurity C)

• 产品号: E650010
• CAS号: 13127-18-9
• 分子式: C37H68N2O13
• 分子量: 748.94142
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Erythromycin A Oxime (Roxithromycin Impurity C)
• IUPAC标准名: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
• IUPAC传统名: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
• 别名: Erythromycin Oxime; 9-Erythromycin 9-Oxime; 9-Erythromycin A Oxime; Roxithromycin Impurity C

产品登记号

• CAS号: 13127-18-9

产品性质

• 外观: Off-White Solid
• 熔点: 159-161°C
• 溶解度: Choroform
• 溶解度: Dichloromethane
• 溶解度: Methanol
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

The major metabolite of Roxithromycin; also an intermediate of Azithromycin. Antibacterial agent. Roxithromycin impurity C.

参考文献

• Ferrero, J., et al.: Drug Metab. Dispos., 18, 441 (1990)
• Gase, C., et al.: J. Antibiot., 44, 313 (1990)
• Markham, A., et al.: Drugs, 48, 297 (1990)
• Jarukamjorn, K., et al.: J. Pharm. Pharmacol., 50, 515 (1990)