6,7-Epoxy Docetaxel(Mixture of Diastereomers)

• 产品号: E589190
• CAS号: 181208-36-6
• 分子式: C43H51NO14
• 分子量: 805.86334

产品别名

• 标题: 6,7-Epoxy Docetaxel(Mixture of Diastereomers)
• IUPAC标准名: (1S,2S,3R,4S,7R,11S,13R,16S)-4-(acetyloxy)-16-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,13-dihydroxy-11,15,18,18-tetramethyl-12-oxo-6,9-dioxapentacyclo[12.3.1.0^3,^1^1.0^4,^7.0^8,^1^0]octadec-14-en-2-yl benzoate
• IUPAC传统名: (1S,2S,3R,4S,7R,11S,13R,16S)-4-(acetyloxy)-16-{[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy}-1,13-dihydroxy-11,15,18,18-tetramethyl-12-oxo-6,9-dioxapentacyclo[12.3.1.0^3,^1^1.0^4,^7.0^8,^1^0]octadec-14-en-2-yl benzoate
• 别名: 3a-(Acetyloxy)-4-(benzoyloxy)-1a,1b,3a,3b,4,5,6,7,10,11,11a,11b-dodecahydro-5,10-dihydroxy-8,11a,12,12-tetramethyl-11-oxo-5,9-methano-3H-cyclodec[3,4]oxireno[5,6]benz[1,2-b]oxet-7-yl Ester; β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic Acid

产品登记号

• CAS号: 181208-36-6

产品详细信息

详细说明 (English)

A taxane derivative modified at 6 and 7 positions for use as antitumor agent.

参考文献

• Gaskin, F., et al.: J. Mol. Biol., 89, 737 (1974)
• Mathew, A.E., et al.: J. Med. Chem., 35, 145 (1974)