Eplerenone

• 产品号: E588775
• CAS号: 107724-20-9
• 分子式: C24H30O6
• 分子量: 414.4914
• 保 存: -20°C Freezer

产品别名

• 标题: Eplerenone
• IUPAC标准名: methyl (2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^1,^1^7.0^2,^7.0^1^1,^1^5]octadecan]-6'-ene-9'-carboxylate
• IUPAC传统名: methyl (2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^1,^1^7.0^2,^7.0^1^1,^1^5]octadecan]-6'-ene-9'-carboxylate
• 别名: Inspra; CGP 30083; γ-Lactone 7-Methyl Ester; (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; Epoxymexrenone; SC-66110

产品登记号

• CAS号: 107724-20-9

产品性质

• 外观: White Solid
• 熔点: 241-243°C
• 溶解度: Chloroform
• 溶解度: Ethyl Acetate
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid rece

参考文献

• de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987)
• Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (1987)
• Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (1987)
• Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (1987)