Eltrombopag

• 产品号: E508000
• CAS号: 496775-61-2
• 分子式: C25H22N4O4
• 分子量: 442.46658
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Eltrombopag
• IUPAC标准名: 3-(3-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2-hydroxyphenyl)benzoic acid
• IUPAC传统名: 3-(3-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxopyrazol-4-ylidene]hydrazin-1-yl}-2-hydroxyphenyl)benzoic acid
• 别名: 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB 497115

产品登记号

• CAS号: 496775-61-2

产品性质

• 外观: Orange to Red Solid
• 熔点: 236-238°C (dec.)
• 溶解度: DMSO
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

参考文献

• Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007)
• Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2007)
• Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2007)