Elacridar

• 产品号: E489000
• CAS号: 143664-11-3
• 分子式: C34H33N3O5
• 分子量: 563.64292
• 保 存: -20°C Freezer

产品别名

• 标题: Elacridar
• IUPAC标准名: N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydroacridine-4-carboxamide
• IUPAC传统名: N-{4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl}-5-methoxy-9-oxo-10H-acridine-4-carboxamide
• 别名: GG 918; N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GW 0918

产品登记号

• CAS号: 143664-11-3

产品性质

• 外观: Yellow Solid
• 熔点: 216-218°C
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport.

参考文献

• Neville, K., et al.: Clin. Cancer Res., 10, 2525 (2004)
• Reardon, D., et al.: J. Clin. Oncol. 23, 9359 (2004)
• Pan, G., et al.: Drug Metab. Dispos., 35, 1165 (2004)