Eflornithine Hydrochloride Monohydrate

• 产品号: E436000
• CAS号: 96020-91-6
• 分子式: C6H15ClF2N2O3
• 分子量: 236.6447064
• 保 存: -20°C Freezer

产品别名

• 标题: Eflornithine Hydrochloride Monohydrate
• IUPAC标准名: 2,5-diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
• IUPAC传统名: vaniqa hydrate hydrochloride
• 别名: MDL 71782; 2-(Difluoromethyl)-DL-ornithine Hydrochloride Hydrate; 2-(Difluoromethyl)ornithine; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine; DFMO; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; Elfornithine; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric Acid

产品登记号

• CAS号: 96020-91-6

产品性质

• 外观: White Solid
• 熔点: >210°C (dec.)
• 溶解度: Water
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.

参考文献

• Bacchi, C.J., et al.: Science, 210, 332 (1980)
• Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1980)
• Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1980)