6α,3'-p-Dihydroxy Paclitaxel

• 产品号: D454200
• CAS号: 157230-10-9
• 分子式: C47H51NO16
• 分子量: 885.90494
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: 6α,3'-p-Dihydroxy Paclitaxel
• IUPAC标准名: (1S,2S,3R,4S,7R,8S,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,8,9-trihydroxy-15-{[(2R,3S)-2-hydroxy-3-(4-hydroxyphenyl)-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: (1S,2S,3R,4S,7R,8S,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,8,9-trihydroxy-15-{[(2R,3S)-2-hydroxy-3-(4-hydroxyphenyl)-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• 别名: (αR,βS)-β-(Benzoylamino)-α,4-dihydroxybenzenepropanoic Acid 6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-3,4,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester

产品登记号

• CAS号: 157230-10-9

产品性质

• 外观: Off-White Solid
• 熔点: 191-194°C
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

The human liver metabοlite of Paclitaxel. Antitumor agent.

参考文献

• Harris, J., et al.: Cancer Res., 54, 4026 (1994)
• Harris, J., et al.: J. Med. Chem., 37, 706 (1994)
• Tolcher, A., et al.: J. Clin. Oncol., 14, 1173 (1994)
• Ohyama, K., et al.: Drug Metab. Dispos., 28, 1303 (1994)