2',3'-Dihydro-7'-methyl-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-6'-carbonitrile

• 产品号: D453360
• CAS号: 58610-64-3
• 分子式: C12H12N2O3
• 分子量: 232.23528

产品别名

• 标题: 2',3'-Dihydro-7'-methyl-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-6'-carbonitrile
• IUPAC标准名: 7'-methyl-5'-oxo-3',5'-dihydro-2'H-spiro[1,3-dioxolane-2,1'-indolizine]-6'-carbonitrile
• IUPAC传统名: 7'-methyl-5'-oxo-2',3'-dihydrospiro[1,3-dioxolane-2,1'-indolizine]-6'-carbonitrile

产品登记号

• CAS号: 58610-64-3

产品性质

• 外观: Grey Solid
• 溶解度: Dimethyl Sulfoxide

产品详细信息

详细说明 (English)

Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.

参考文献

• Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986)
• Miller, K.D., et al.: Invest. New Drugs, 22, 69 (1986)
• Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (1986)
• Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005)