rac 8,14-Dihydroxy Efavirenz

• 产品号: D452800
• CAS号: 1189909-96-3
• 分子式: C14H9ClF3NO4
• 分子量: 347.6737696
• 保 存: -20°C Freezer

产品别名

• 标题: rac 8,14-Dihydroxy Efavirenz
• IUPAC标准名: 6-chloro-8-hydroxy-4-[2-(1-hydroxycyclopropyl)ethynyl]-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
• IUPAC传统名: 6-chloro-8-hydroxy-4-[2-(1-hydroxycyclopropyl)ethynyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
• 别名: 6-Chloro-1,4-dihydro-8-hydroxy-4-[(1-hydroxycyclopropyl)ethynyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

产品登记号

• CAS号: 1189909-96-3

产品性质

• 外观: White Solid
• 熔点: >199°C (dec.)
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A metabolite of Efavirenz (E425000) (secondary metabolism).

参考文献

• Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994)
• Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1994)
• Langmann, P., et al.: Eur. J. Med. Res., 7, 309 (1994)
• Chang, T., et al.: Drug Metab. Dispos., 31, 7 (1994)