trans (2,3)-Dihydro Tetrabenazine

• 产品号: D449655
• CAS号: 171598-74-6
• 分子式: C19H29NO3
• 分子量: 319.43846
• 保 存: Refrigerator

产品别名

• 标题: trans (2,3)-Dihydro Tetrabenazine
• IUPAC标准名: (2S,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol
• IUPAC传统名: (2S,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol
• 别名: (2α,3β,11bβ)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2R,3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol

产品登记号

• CAS号: 171598-74-6

产品性质

• 外观: white Solid
• 熔点: 167-170°C
• 溶解度: Chloroform
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A metabolite of Tetrabenazine in vivo. The trans izomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.

参考文献

• Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995)
• Perera, R., et al.: J. Med. Chem., 46, 2599 (1995)
• Mager, D., et al.: J. Pharm. Sci., 94, 2475 (1995)
• Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (1995)