3,4-Dihydro-7-hydroxyquinoline-2(1H)-one

• 产品号: D449145
• CAS号: 22246-18-0
• 分子式: C9H9NO2
• 分子量: 163.17326

产品别名

• 标题: 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one
• IUPAC标准名: 7-hydroxy-1,2,3,4-tetrahydroquinolin-2-one
• IUPAC传统名: 7-hydroxy-3,4-dihydro-1H-quinolin-2-one
• 别名: 7-Hydroxycarbostyril; 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone; 3,4-Dihydro-7-hydroxy-carbostyril; 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

产品登记号

• CAS号: 22246-18-0

产品性质

• 外观: Pale Yellow Powder
• 熔点: 233-235°C
• 溶解度: DMSO
• 溶解度: Methanol

产品详细信息

详细说明 (English)

An antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000).

参考文献

• Bouchard, B., et al.: J. Exp. Med., 169, 2029 (1989)
• Kim, Y., et al.: J. Biol. Chem., 277, 16340 (1989)
• Cho, S., et al.: Bioorg. Med. Chem. Lett., 16, 2682 (1989)