Dihydro Finasteride

• 产品号: D448975
• CAS号: 98319-24-5
• 分子式: C23H38N2O2
• 分子量: 374.56002
• 保 存: Refrigerator

产品别名

• 标题: Dihydro Finasteride
• IUPAC标准名: (1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecane-14-carboxamide
• IUPAC传统名: (1S,2R,7R,10S,11S,14S,15S)-N-tert-butyl-2,15-dimethyl-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecane-14-carboxamide
• 别名: (5α,17β)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrostane-17-carboxamide; N-(tert-Butyl)-3-oxo-4-aza-5α-androstane-17β-carboxamide; 3-Oxo-4-aza-5α-androstan-17β-carboxylic acid N-(tert-butyl)amide; Dihydroproscar; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-Dimethylethyl)hexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-N-(1,1-Dimethylethyl)hexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; 1,2-Dihydrofinasteride

产品登记号

• CAS号: 98319-24-5

产品性质

• 外观: White Solid
• 熔点: 276-278°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

The reduced product of Finasteride (F342000): a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process.

参考文献

• Bull, H.G. et al.: Am. J. Chem. Soc., 118, 2359 (1996)
• Liang, T. et al.: Endocrinol., 117, 571 (1996)
• Ellsworth, K.P. et al.: J. Steroid Bioche. Mol. Biol., 66, 271 (1996)