6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(3,3,3-d3-propionyloxy)-androsta-1,4-diene-17β-carbothioic Acid

• 产品号: D445767
• 分子式: C24H30F2O5S
• 分子量: 468.5538064

产品别名

• 标题: 6α,9α-Difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(3,3,3-d3-propionyloxy)-androsta-1,4-diene-17β-carbothioic Acid
• IUPAC标准名: (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-[(3,3,3-^2H₃)propanoyloxy]tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-14-carbothioic S-acid
• IUPAC传统名: (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-[(3,3,3-^2H₃)propanoyloxy]tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-14-carbothioic S-acid
• 别名: (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carbothioic-d3 Acid

产品性质

• 外观: White Solid
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: DMF
• 溶解度: Ethanol
• 溶解度: Ethyl Acetate
• 溶解度: Methanol

产品详细信息

详细说明 (English)

An intermediate in the synthesis of Fluticasone Propionate.

参考文献

• Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990)
• Mitchison, H.C., et al.: Gut, 32, 260 (1990)
• Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)