(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

• 产品号: D446035
• CAS号: 376608-71-8
• 分子式: C17H17F2NO3
• 分子量: 321.3185864
• 保 存: Refrigerator

产品别名

• 标题: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
• IUPAC标准名: (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine; (2R)-2-hydroxy-2-phenylacetic acid
• IUPAC传统名: (-)-mandelic acid; (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
• 别名: (αR)-α-Hydroxybenzeneacetic Acid compd. with (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine

产品登记号

• CAS号: 376608-71-8

产品性质

• 外观: Off-White Solid
• 熔点: 158-162°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists for the prevention of thrombosis.

参考文献

• Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007)