cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol

• 产品号: D435930
• CAS号: 61397-58-8
• 分子式: C14H14Cl2N2O3
• 分子量: 329.17856
• 保 存: Refrigerator

产品别名

• 标题: cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
• IUPAC标准名: [(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
• IUPAC传统名: [(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
• 别名: (2R,4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol

产品登记号

• CAS号: 61397-58-8

产品性质

• 外观: White Solid
• 熔点: 130-132°C
• 溶解度: Chloroform
• 溶解度: DMSO
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa).

参考文献

• Power, E.C. et al.: Bioorg. Med. Chem., 16, 887 (2006)
• Heeres, J. et al.: J. Med. Chem., 22, 1003 (2006)