cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate

• 产品号: D435718
• CAS号: 134071-44-6
• 分子式: C21H20Cl2N2O5S
• 分子量: 483.3649
• 保 存: -20°C Freezer

产品别名

• 标题: cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate
• IUPAC标准名: [2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzene-1-sulfonate
• IUPAC传统名: [2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate
• 别名: (2R,4R)-rel-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol 4-(4-Methylbenzenesulfonate)

产品登记号

• CAS号: 134071-44-6

产品性质

• 外观: Off-White Solid
• 熔点: 120-122°C
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

An intermediate in the synthesis of the drug Ketoconazole (K186000).

参考文献

• McManus, O., et al.: Biochemistry, 32, 6128 (1993)
• Olesen, S., et al.: Eur. J. Pharmacol., 251, 53 (1993)
• Assano, M., et al.: J. Pharm. Exp. Ther., 275, 775 (1993)
• Hewawasam, P., et al.: J. Med. Chem., 45, 1487 (1993)