L-Dicentrine

• 产品号: D431500
• CAS号: 28832-07-7
• 分子式: C20H21NO4
• 分子量: 339.38504

产品别名

• 标题: L-Dicentrine
• IUPAC标准名: (12R)-16,17-dimethoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.0^2,^6.0^8,^2^0.0^1^4,^1^9]icosa-1(20),2(6),7,14,16,18-hexaene
• IUPAC传统名: (12R)-16,17-dimethoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.0^2,^6.0^8,^2^0.0^1^4,^1^9]icosa-1(20),2(6),7,14,16,18-hexaene
• 别名: (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; NSC 251699; (R)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; (R)-(-)-Dicentrine; 9,10-Dimethoxy-1,2-(methylenedioxy)-6aβ-aporphine; (-)-Dicentrine

产品登记号

• CAS号: 28832-07-7

产品详细信息

详细说明 (English)

A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive anta

参考文献

• Li, H. et al.: Zhong. Zhon. Zaz., 25, 426 (2000)
• Li, M. et al.: Acad. J. Kun. Med. Coll., 1003 (2000)
• Teng, C.M. et al.: Brit, J. Pharmacol., 104, 651 (2000)