3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxy-8-[(3-(methyl-d3)-8-methyl-3H-imidazo[4,5-f]quinoxalin-2-yl)amino]guanosine

• 产品号: D429412
• 分子式: C33H50N10O4Si2
• 分子量: 706.9857
• 保 存: Refrigerator

产品别名

• 标题: 3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxy-8-[(3-(methyl-d3)-8-methyl-3H-imidazo[4,5-f]quinoxalin-2-yl)amino]guanosine
• IUPAC标准名: 2-amino-9-[(2R,4S,5R)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-8-{[3-(^2H₃)methyl-8-methyl-3H-imidazo[4,5-f]quinoxalin-2-yl]amino}-6,9-dihydro-1H-purin-6-one
• IUPAC传统名: 2-amino-9-[(2R,4S,5R)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-8-{[3-(^2H₃)methyl-8-methylimidazo[4,5-f]quinoxalin-2-yl]amino}-1H-purin-6-one
• 别名: N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-d3

产品性质

• 外观: Yellow Solid
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: Dimethyl Sulfoxide
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

dG-C8-MeIQx-d3 (D239617) derivative. MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development.

参考文献

• Ohshima, H., et al.: Mutat. Res., 305, 253 (1994)
• Pais, P., et al.: J. Agric. Food Chem., 47, 1098 (1994)
• Lakshmi, V., et al.: Chem. Res. Toxicol., 18, 1038 (1994)