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Dexamethasone Phosphate

产品号 D298835 公司名称 Toronto Research Chemicals
CAS号 312-93-6 公司网站 http://www.trc-canada.com
分子式 C22H30FO8P 电 话 +1 (416) 665-9696
分子量 472.4409642 传 真 +1 (416) 665-4439
纯 度 电子邮件 info@trc-canada.com
保 存 Chembase数据库ID: 166727

产品价格信息

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产品别名

标题
Dexamethasone Phosphate
IUPAC标准名
{2-[(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}phosphonic acid
IUPAC传统名
2-[(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethoxyphosphonic acid
别名
Wymesone
9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Phosphate
Betnelan Phosphate
Dexamethasone Orthophosphate
Micromethason
(11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione
Dexamethasone 21-Dihydrogen Phosphate
Dexamethasone 21-Phosphate

产品登记号

CAS号 312-93-6

产品性质

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产品详细信息

详细说明 (English)
A pro-drug of Dexamethasone (D298800), an anti-inflammatory glucocorticoid. It was found that liposomal DXM-P inhibited both chronic inflammation and joint destruction, whereas free DXM-P failed to prevent joint destruction.

参考文献

  • Kodelja, V., et al.: J. Immunol., 160, 1411 (1998)
  • Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (1998)
  • Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (1998)
  • Martinez, F., et al.: Front Biosci., 13, 453 (1998)