N-Desmethyl Tadalafil

• 产品号: D293800
• CAS号: 171596-36-4
• 分子式: C21H17N3O4
• 分子量: 375.37738

产品别名

• 标题: N-Desmethyl Tadalafil
• IUPAC标准名: (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraene-4,7-dione
• IUPAC传统名: (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraene-4,7-dione
• 别名: (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione; Nortadalafil; (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

产品登记号

• CAS号: 171596-36-4

产品详细信息

详细说明 (English)

A N-desmethyl analogue of the human PDE5 inhibitor Tadalafil (T004500). A potential antiplasmodial drug.

参考文献

• Beghyn, T. et al.: Bioorg. Med. Chem. Lett., 17, 789 (2007)
• Daugan, A. et al.: J. Med. Chem., 46, 4533 (2007)