Desisobutyryl Ciclesonide-d11 (Mixture of Diastereomers)

• 产品号: D290102
• 分子式: C28H38O6
• 分子量: 470.59772
• 保 存: -20°C Freezer

产品别名

• 标题: Desisobutyryl Ciclesonide-d11 (Mixture of Diastereomers)
• IUPAC标准名: (1S,2S,4R,8S,9S,11S,12S,13R)-6-(^2H₁₁)cyclohexyl-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-14,17-dien-16-one
• IUPAC传统名: (1S,2S,4R,8S,9S,11S,12S,13R)-6-(^2H₁₁)cyclohexyl-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-14,17-dien-16-one
• 别名: CIC-AP-d11; Ciclesonide active principle-d11; (11β,16α)-16,17-[[(R/S)-Cyclohexyl-d11-methylene]bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

产品性质

• 外观: White Solid
• 熔点: 215-222°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma. This compound is a mixture of diastereomers at the cyclohexyl acetal.

参考文献

• Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002)
• Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2002)
• Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).