Desethyl Sildenafil

• 产品号: D289600
• CAS号: 139755-91-2
• 分子式: C20H26N6O4S
• 分子量: 446.52324
• 保 存: Refrigerator

产品别名

• 标题: Desethyl Sildenafil
• IUPAC标准名: 5-{2-hydroxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
• IUPAC传统名: 5-[2-hydroxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
• 别名: 5-[2-Hydroxy-5-(4-methylpiperazinylsulphonyl)phenyl]1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyramidin-7-one; 5-[2-Hydroxy-5-[[4-(methyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one

产品登记号

• CAS号: 139755-91-2

产品性质

• 外观: Off-White Solid
• 熔点: 279-281°C (dec.)
• 溶解度: Aqueous Base
• 溶解度: DMSO (Sparingly)
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.

参考文献

• Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996)
• Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)