N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride

• 产品号: D288740
• CAS号: 111974-74-4
• 分子式: C17H17N3S
• 分子量: 295.40198
• 保 存: -20°C Freezer

产品别名

• 标题: N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride
• IUPAC标准名: 10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
• IUPAC传统名: 10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
• 别名: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine, Dihydrochloride, DBTP,

产品登记号

• CAS号: 111974-74-4

产品性质

• 外观: Off-White to Pale-Yellow Solid
• 熔点: 287-292°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.

参考文献

• DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001)
• Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2001)
• Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2001)
• Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2001)