4-Desacetyl Vincristine Methosulfate

• 产品号: D288729
• CAS号: 3704-01-6
• 分子式: C45H58N4O13S
• 分子量: 895.02602
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: 4-Desacetyl Vincristine Methosulfate
• IUPAC标准名: methoxysulfonic acid methyl (1R,9R,10S,11R,12R,19R)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10,11-dihydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
• IUPAC传统名: methyl (1R,9R,10S,11R,12R,19R)-12-ethyl-4-[(1S,13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10,11-dihydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraene-10-carboxylate methyl sulfate
• 别名: 4-Deacetylvincristine Methosulfate; 4-Deacetyl Leurocristine Methosulfate; 4-Desacetylvincristine Methosulfate; O4-Deacetyl-22-oxo-vincaleukoblastine Methosulfate

产品登记号

• CAS号: 3704-01-6

产品性质

• 外观: White to Off-White Solid
• 熔点: >300°C (dec.)
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A metabolite of Vincristine in bile. Antitumor agent used against human colon carcinoma.

参考文献

• Houghton, J.A., et al.: Anal. Biochem., 134, 450 (1983)
• Sethi, V.S., et al.: Cancer Res., 45, 5386 (1983)
• Horton, J.K., et al.: Biochem. Pharmacol., 38, 1727 (1983)