4-Desacetyl Vinblastine Methosulfate

• 产品号: D288440
• 分子式: C45H60N4O12S
• 分子量: 881.0425
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: 4-Desacetyl Vinblastine Methosulfate
• IUPAC标准名: methoxysulfonic acid methyl (9R,10S,11R,12R,19R)-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate
• IUPAC传统名: methyl (9R,10S,11R,12R,19R)-12-ethyl-4-[(1R,13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^4,^1^2.0^5,^1^0]nonadeca-4(12),5,7,9-tetraen-13-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2,4,6,13-tetraene-10-carboxylate methyl sulfate
• 别名: O4-Deacetyl-vincaleukoblastine Methosulfate; Deacetylvinblastine Methosulfate; 4-Deacetylvinblastine Methosulfate

产品性质

• 外观: Off-White Solid
• 熔点: >300°C (dec.)
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A pro-drug of Vinblastine. Antitumor agent used for treatment of prostate cancer.

参考文献

• Raghavan, D., et al.: Eur. J. Cancer, 33, 566 (1997)
• Brady, S.F., et al.: J. Med. Chem., 45, 4706 (1997)