2'-Deoxy-6-thio Guanosine

• 产品号: D281650
• CAS号: 789-61-7
• 分子式: C10H13N5O3S
• 分子量: 283.30692

产品别名

• 标题: 2'-Deoxy-6-thio Guanosine
• IUPAC标准名: 2-amino-9-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purine-6-thione
• IUPAC传统名: 2-amino-9-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
• 别名: β-Thioguanine Deoxyriboside; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine; NSC 71261; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione; Thioguanine Deoxyriboside; 2'-Deoxythioguanosine; 2'-Desoxy-6-thioguanosine; TGdR

产品登记号

• CAS号: 789-61-7

产品详细信息

详细说明 (English)

Guanosine (G837900) derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.

参考文献

• Momparler, R.L. et al.: Cancer Treat. Rep., 62, 135 (1978)
• Krynetskaia, N.F. et al.: Mol. Pharmacol., 56, 841 (1978)