3'-Deoxy-3'-fluorothymidine-5'-monophosphate-d3 Disodium Salt

• 产品号: D235482
• 分子式: C10H12FN2Na2O7P
• 分子量: 368.1631842
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: 3'-Deoxy-3'-fluorothymidine-5'-monophosphate-d3 Disodium Salt
• IUPAC标准名: disodium [(2R,3S,5R)-3-fluoro-5-[5-(^2H₃)methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methyl phosphate
• IUPAC传统名: disodium [(2R,3S,5R)-3-fluoro-5-[5-(^2H₃)methyl-2,4-dioxo-3H-pyrimidin-1-yl]oxolan-2-yl]methyl phosphate
• 别名: 3'-Fluoro-3'-deoxythymidine-d3 Monophosphate Disodium; 2',3'-Dideoxy-3'-fluoro-5-methyluridine-d3 5'-(Dihydrogen Phosphate) Disodium; 3'-Deoxy-3'-fluoro-5'-thymidylic Acid-d3 Disodium; 3'-Deoxy-3'-fluoro-thymidine-d3 Monophosphate Disodium

产品性质

• 外观: White Solid
• 熔点: 169-171°C
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase.

参考文献

• Jong, A., et al.: J. Biol. Chem., 259, 11052 ( 1984), Choi, Y., et al.: J. Med. Chem., 43, 2538 (2000)
• Stokstad, E., et al.: Science, 287, 2391 (2000)
• Li de La Sierra, I., et al.: J. Mol. Biol., 311, 87 (2000)