3-Demethyl Thiocolchicine-d3

• 产品号: D231332
• 分子式: C21H23NO5S
• 分子量: 401.47602
• 保 存: Refrigerator

产品别名

• 标题: 3-Demethyl Thiocolchicine-d3
• IUPAC标准名: N-[(10S)-5-hydroxy-3,4-dimethoxy-14-(methylsulfanyl)-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl](^2H₃)acetamide
• IUPAC传统名: N-[(10S)-5-hydroxy-3,4-dimethoxy-14-(methylsulfanyl)-13-oxotricyclo[9.5.0.0^2,^7]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl](^2H₃)acetamide
• 别名: N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide-d3; NSC 361792-d3; 2-Demethylthio-colchicine-d3; 3-Demethylthiocolchicine-d3; 3-Desmethylthiocolchicine-d3; 3-O-Demethylthiocolchicine-d3

产品性质

• 外观: Yellow Solid
• 熔点: >246°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A Thiocolchicine metabolite, used in therapy as an antitunor, antiinflammatory and immunosuppressive agent.

参考文献

• Trellu, M., et al.: Fund. Clin. Pharmacol., 18, 493 (2004)
• Nakagawa-Goto, K., et al.: Bioorg. Med. Chem. Lett., 15, 235 (2004)
• Gelmi, M., et al.: J. Med. Chem., 50, 2245 (2004)