4'-Demethyl Homoharringtonine

• 产品号: D231150
• CAS号: 98599-84-9
• 分子式: C28H37NO9
• 分子量: 531.59468

产品别名

• 标题: 4'-Demethyl Homoharringtonine
• IUPAC标准名: (3R)-3,7-dihydroxy-3-({[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^2,^6.0^6,^1^0.0^1^5,^1^9]icosa-1(20),4,13,15(19)-tetraen-3-yl]oxy}carbonyl)-7-methyloctanoic acid
• IUPAC传统名: (3R)-3,7-dihydroxy-3-({[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^2,^6.0^6,^1^0.0^1^5,^1^9]icosa-1(20),4,13,15(19)-tetraen-3-yl]oxy}carbonyl)-7-methyloctanoic acid
• 别名: 5'-Des-O-methylhomoharringtonine; Cephalotaxine 4-Hydrogen (2R)-2-Hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (Ester)

产品登记号

• CAS号: 98599-84-9

产品详细信息

详细说明 (English)

A metabolite of Homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia.

参考文献

• Powell, R., et al.: J. Pharm. Sci., 61, 1227 (1972)
• Ohnuma, T., et al.: J. Clin. Oncol., 3, 604 (1972)
• Scudiero, D., et al.: Cancer Res., 48, 4827 (1972)
• Zhou, D., et al.: Bull. Cancer, 82, 987 (1972)
• Kantarjian, H., et al.: Cancer, 92, 1591 (1972)