4-Dehydroxy-5-hydroxy Ritonavir

• 产品号: D230645
• CAS号: 202816-62-4
• 分子式: C37H48N6O5S2
• 分子量: 720.94422

产品别名

• 标题: 4-Dehydroxy-5-hydroxy Ritonavir
• IUPAC标准名: 1,3-thiazol-5-ylmethyl N-[(2S,4S,5S)-4-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate
• IUPAC传统名: 1,3-thiazol-5-ylmethyl N-[(2S,4S,5S)-4-hydroxy-5-[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-3-methylbutanamido]-1,6-diphenylhexan-2-yl]carbamate
• 别名: Ritonavir Impurity I; (3S,5S,6S,9S)-5-Hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-Thiazolylmethyl Ester; (5S,8S,9S,11S)-9-Hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic Acid 5-Thiazolylmethyl Ester

产品登记号

• CAS号: 202816-62-4

产品详细信息

详细说明 (English)

4-Dehydroxy-5-Hydroxy Ritonavir is an impurity of the selective HIV protease inhibitor Ritonavir (R535000).

参考文献

• Kempf, D.J. et al.: J. Med. Chem., 41, 602 (1998)
• Mekapati, S.B. et al.: J. Enzyme Inhib., 16, 185 (1998)