Daunorubicinol (Mixture of Diastereomers)

• 产品号: D194510
• 分子式: C27H31NO10
• 分子量: 529.53574
• 保 存: -20°C Freezer

产品别名

• 标题: Daunorubicinol (Mixture of Diastereomers)
• IUPAC标准名: (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-[(1R)-1-hydroxyethyl]-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione
• IUPAC传统名: dihydrodaunomycin
• 别名: Leukaemomycin D; 13-Dihydrodaunorubicin; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-[1-hydroxyethyl]-1-methoxy-5,12-naphthacenedione; Duborimycin

产品性质

• 外观: Red Solid
• 熔点: 179-181°C
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A metabolite of Daunorubicin. Used as an antineoplastic. Complexes with DNA. Inhibits DNA and RNA synthesis.

参考文献

• Mizuno, N.S., et al.: Cancer Res., 35, 1542 (1975)
• Munger, C., et al.: Cancer Res., 48, 2404 (1975)
• Kobayashi, Y., et al.: J. Biol. Chem., 275, 17639 ( 2000), Burke, B., et al.: Cardiovasc. Toxicol., 2, 41 (1975)