Daptomycin

• 产品号: D193350
• CAS号: 103060-53-3
• 分子式: C72H101N17O26
• 分子量: 1620.67064
• 保 存: -20°C Freezer

产品别名

• 标题: Daptomycin
• IUPAC标准名: (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2S)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid
• IUPAC传统名: (3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaazacyclohentriacontan-30-yl]carbamoyl}-3-[(2S)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid
• 别名: Cubicin; Ly-146032; Cidecin

产品登记号

• CAS号: 103060-53-3

产品性质

• 外观: Off-White to Light Yellow Solid
• 熔点: 202-204°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.

参考文献

• Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987)
• Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1987)