Cyclosporin A-13C2,d4 (Major)

• 产品号: C988901
• 分子式: C32H65N3O4
• 分子量: 557.86150968
• 保 存: Refrigerator

产品别名

• 标题: Cyclosporin A-13C2,d4 (Major)
• IUPAC标准名: (2S)-N-[(1S)-1-{[(5R,6R,8E)-5-hydroxy-6-methyl-3-oxo(9,10-^1^3C₂,9,10,10,10-^2H₄)dec-8-en-4-yl](methyl)carbamoyl}-2-methylpropyl]-4-methyl-2-(methylamino)pentanamide; bis(butane)
• IUPAC传统名: (2S)-N-[(1S)-1-{[(5R,6R,8E)-5-hydroxy-6-methyl-3-oxo(9,10-^1^3C₂,9,10,10,10-^2H₄)dec-8-en-4-yl](methyl)carbamoyl}-2-methylpropyl]-4-methyl-2-(methylamino)pentanamide; bis(butane)
• 别名: Sandimmun(e)-13C2,d4; Optimmune-13C2,d4; Ciclosporin-13C2,d4; Cyclosporine-13C2,d4; Atopica-13C2,d4; Neoral-13C2,d4; Restasis-13C2,d4

产品性质

• 外观: White Solid
• 熔点: 140-145°C
• 溶解度: Acetone
• 溶解度: Benzene
• 溶解度: Chloroform
• 溶解度: Ethanol
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

参考文献

• van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988)
• Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (1988)
• Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (1988)