(5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-6-(methylamino)-morphinan-3,14-diol

• 产品号: C988740
• CAS号: 102869-99-8
• 分子式: C21H28N2O3
• 分子量: 356.45862
• 保 存: Refrigerator

产品别名

• 标题: (5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-6-(methylamino)-morphinan-3,14-diol
• IUPAC标准名: (1S,5R,13R,14S,17S)-4-(cyclopropylmethyl)-14-(methylamino)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol
• IUPAC传统名: (1S,5R,13R,14S,17S)-4-(cyclopropylmethyl)-14-(methylamino)-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7(18),8,10-triene-10,17-diol
• 别名: Des-N-(3-furanyl-2-propenamide) Nalfurafine

产品登记号

• CAS号: 102869-99-8

产品性质

• 外观: White Solid
• 溶解度: Dimethyl Sulfoxide
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Opioid receptor antagonist. Used in the preparation of opioid κ-agonist TRK-820 and other related compounds.

参考文献

• Mohamed, M.S. et al.: J. Med. Chem. 29, 1551 (1986)
• Nagase, H. et al.: Chem. Pharm. Bull. 46, 366 (1998).