(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide

• 产品号: C988700
• CAS号: 697287-41-5
• 分子式: C23H25FN2O2
• 分子量: 380.4552032

产品别名

• 标题: (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)acrylamide
• IUPAC标准名: (2E)-N-[(1S)-1-[4-(cyclopropylmethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)prop-2-enamide
• IUPAC传统名: (2E)-N-[(1S)-1-[4-(cyclopropylmethyl)-2,3-dihydro-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)prop-2-enamide
• 别名: N-[(1S)-1-[4-(Cyclopropylmethyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]ethyl]-3-(2-fluorophenyl)-2-propenamide

产品登记号

• CAS号: 697287-41-5

产品性质

• 外观: White to Off-White Solid
• 熔点: 180-182°C
• 溶解度: Acetone
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 溶解度: Methanol

产品详细信息

详细说明 (English)

A potent and efficacious KCNQ2 opener which inibits induced hyperexcitability of rat hippocampal neurons.

参考文献

• Wu, Y-J., et al.: Bioorg & Medicinal Chemistry Letters, 14, 1991 (2004)