Cyclophosphamide-d4

• 产品号: C988582
• CAS号: 173547-45-0
• 分子式: C7H15Cl2N2O2P
• 分子量: 261.085961
• 保 存: -20°C Freezer

产品别名

• 标题: Cyclophosphamide-d4
• IUPAC标准名: 2-[bis(2-chloroethyl)amino](4,4,5,5-^2H₄)-1,3,2λ^5-oxazaphosphinan-2-one
• IUPAC传统名: 2-[bis(2-chloroethyl)amino](4,4,5,5-^2H₄)-1,3,2λ^5-oxazaphosphinan-2-one
• 别名: Genoxal-d4; N,N-Bis(2-chloroethyl)tetrahydro-4,5-d2-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide; Cytoxan-d4; NSC 26271-d4; Cycloblastin-d4; Endoxan-d4; Cyclostin-d4; Hexadrin-d4; Mitoxan-d4

产品登记号

• CAS号: 173547-45-0

产品性质

• 外观: White to Off-White Solid
• 熔点: 41-45°C
• 溶解度: Alcohol
• 溶解度: Benzene
• 溶解度: Chloroform
• 溶解度: Dioxane
• 溶解度: Ethylene Glycol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This sub

参考文献

• Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962)
• Fraiser, L.H., et al.: Drugs, 42, 781 (1962)
• Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1962)