CUR 61414

• 产品号: C835000
• CAS号: 334998-36-6
• 分子式: C31H42N4O5
• 分子量: 550.68898
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: CUR 61414
• IUPAC标准名: N-[(3S,5S)-1-(2H-1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
• IUPAC传统名: N-[(3S,5S)-1-(2H-1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
• 别名: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide

产品登记号

• CAS号: 334998-36-6

产品性质

• 外观: Pale Yellow Solid
• 熔点: 35-40°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

CUR 61414 is a proline derivative as mediator of hedgehog signaling pathways for pharmaceutical and cosmetic uses. CUR 61414 is a Nucleoside analog. CUR 61414 is an antimetabolite antitumor combination Gemcitabine cancer treatment.

参考文献

• Van der Riet, P., et al.: Cancer Res., 54, 25 (1994)
• Hahn, H., et al.: Cell, 85, 841 (1994)
• Johnson, R., et al.: Science, 272, 1668 (1994)
• Ingham, P., et al.: Genes Dev., 15, 3059 (1994)