Coptisine Chloride

• 产品号: C685500
• CAS号: 6020-18-4
• 分子式: C19H14ClNO4
• 分子量: 355.77176
• 保 存: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品别名

• 标题: Coptisine Chloride
• IUPAC标准名: 5,7,17,19-tetraoxa-13λ^5-azahexacyclo[11.11.0.0^2,^1^0.0^4,^8.0^1^5,^2^3.0^1^6,^2^0]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaen-13-ylium chloride
• IUPAC传统名: coptisine chloride
• 别名: 7,8,13,13a-Tetradehydro-2,3:9,10-bis(methylenedioxy)berbinium Chloride; 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium Chloride; Coptisine Chloride

产品登记号

• CAS号: 6020-18-4

产品性质

• 外观: Orange Brown Solid
• 熔点: >258°C (dec.)
• 溶解度: DMSO (Sparingly)
• 保存条件: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis). A bacterial collagenase inhibitor. Coptisine has been found to reversibly inhibit Monoamine oxidase A in mice, pointing to a potential role as a natural antidepressant.

参考文献

• Blaney, W., et al.: Physiol. Entomol., 12, 281 (1987)
• Sethi, M., et al.: J. Pharm. Sci., 72, 538 (1987)
• Yahara, S., et al.: Chem. Pharm. Bull., 33, 527 (1987)