C8 Ceramide

• 产品号: C262700
• CAS号: 74713-59-0
• 分子式: C26H51NO3
• 分子量: 425.68804
• 保 存: -20°C Freezer

产品别名

• 标题: C8 Ceramide
• IUPAC标准名: N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
• IUPAC传统名: N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
• 别名: N-Octanoyl-C18-sphingosine; D-erythro-N-Octanoylsphingosine; N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]octanamide; N-Octanoyl-D-erythro-sphingosine; N-Octanoylsphingosine; [R-[R*,S*-(E)]]-N-[2-Hydroxy-1-(hydroxymethyl)-3-heptadecenyl]octanamide

产品登记号

• CAS号: 74713-59-0

产品性质

• 外观: Off White Solid
• 熔点: 68-70°C
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis.

参考文献

• Mathias, S., et al.: Proc. Natl. Sci. USA, 88, 10009 (1991)
• Mathias, S., et al.: Science, 259, 519 (1991)
• Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994)