C6 Ceramide-13C2,d2

• 产品号: C262602
• 分子式: C24H47NO3
• 分子量: 399.62018968
• 保 存: -20°C Freezer

产品别名

• 标题: C6 Ceramide-13C2,d2
• IUPAC标准名: N-[(2R,3R,4E)-1,3-dihydroxy(1,2-^1^3C₂,1,1-^2H₂)octadec-4-en-2-yl]hexanamide
• IUPAC传统名: N-[(2R,3R,4E)-1,3-dihydroxy(1,2-^1^3C₂,1,1-^2H₂)octadec-4-en-2-yl]hexanamide
• 别名: Caproyl Ceramide-13C2,d2; N-Hexanoy-D-sphingosine-13C2,d2; N-Caproyl-D-sphingosine-13C2,d2

产品性质

• 外观: Off-White Solid
• 熔点: 69-72°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway

参考文献

• Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993)
• Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993)
• Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1993)